Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749887 | 0.90 | CNR2 (0.35) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL10249525 | 0.88 | LMNA (0.38) | SMN1; SMN2CYP1A2CYP2C9NFKB1HPGD | |
| SCHEMBL12401084 | 0.84 | LTA4H (0.37) | CETP | |
| SCHEMBL14445705 | 0.81 | HTT (0.39) | SMN1; SMN2CYP1A2NFKB1HPGDLMNA | |
| SCHEMBL18563868 | 0.78 | LTA4H (0.35) | CETP | |
| SCHEMBL18563871 | 0.77 | LTA4H (0.34) | CYP1A2CYP2C9CETP | |
| SCHEMBL17753742 | 0.77 | DRD2 (0.41) | SMN1; SMN2CYP1A2CYP2C9CNR2DRD2 | |
| SCHEMBL17753737 | 0.75 | DRD2 (0.40) | CYP1A2CYP2C9CNR2HSD11B1DRD2 | |
| SCHEMBL12680254 | 0.74 | ESR1 (0.34) | SMN1; SMN2HPGDCETPLMNAMEN1 | |
| SCHEMBL3481678 | 0.73 | LTA4H (0.36) | CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519082-B2 | Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| US-20120100474-A1 | POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |