SCHEMBL10249565

SCHEMBL10249565

C[Si](C)(CCc1ccc(O)cc1)O[Si](C)(C)CCc1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.52
ESR2 Q92731 2/20 0.52
CA2 P00918 1/20 0.52
CALM1 P0DP23 1/20 0.46
TMEM97 Q5BJF2 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
ADRA2A P08913 3/20 0.45
SLC6A2 P23975 3/20 0.45
HTR1A P08908 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTR3A P46098 1/20 0.45
BACE1 P56817 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
F13A1 P00488 1/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A4 P31645 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12713552 0.92 CA2 (0.48) ESR1ESR2CA2CALM1TMEM97
SCHEMBL12713553 0.89 ESR1 (0.53) ESR1ESR2CA2CALM1TMEM97
SCHEMBL8999888 0.88 CALM1 (0.52) ESR1ESR2CA2CALM1TMEM97
SCHEMBL8999982 0.86 ESR1 (0.53) ESR1ESR2CA2CALM1TMEM97
SCHEMBL13324786 0.86 ESR1 (0.50) ESR1ESR2CA2CALM1TMEM97
SCHEMBL10249606 0.82 ESR1 (0.58) ESR1ESR2CA2CALM1KDM4E
SCHEMBL14522310 0.82 CALM1 (0.46) ESR1ESR2CA2CALM1KDM4E
SCHEMBL12574830 0.81 CALM1 (0.49) ESR1ESR2CA2CALM1TMEM97
SCHEMBL8999896 0.81 CALM1 (0.49) ESR1ESR2CA2CALM1TMEM97
SCHEMBL9231420 0.81 CYP1A2 (0.46) ALDH1A1TAAR1ACHEKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846281-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-09-30 US disclosed
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 US disclosed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 US disclosed
US-20110158683-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-06-30 US disclosed
US-20070083026-A1 Polyarylate-siloxane copolymers GENERAL ELECTRIC COMPANY (US) 2007-04-12 US disclosed