Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020769 | 0.82 | SPHK2 (0.37) | HRH3CDK2 | |
| SCHEMBL2020772 | 0.82 | SPHK2 (0.37) | HRH3CDK2 | |
| SCHEMBL1023537 | 0.81 | MYC (0.35) | CDK2 | |
| SCHEMBL12635793 | 0.81 | SLC6A9 (0.36) | — | |
| SCHEMBL2025538 | 0.79 | LTA4H (0.44) | KCNH2 | |
| SCHEMBL2025542 | 0.79 | LTA4H (0.44) | KCNH2 | |
| SCHEMBL2023375 | 0.78 | KDM4E (0.41) | HRH3 | |
| SCHEMBL2023377 | 0.78 | KDM4E (0.41) | HRH3 | |
| SCHEMBL1347559 | 0.76 | ALOX15 (0.48) | HRH3CDK2 | |
| SCHEMBL1024539 | 0.74 | CDK2 (0.41) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275414-B1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | KYORIN SEIYAKU KK (JP) | 2015-06-10 | — | — | EP | disclosed |
| EP-2275414-A1 | CYCLOPENTYLACRYLIC ACID AMIDE DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2011-01-19 | — | — | EP | disclosed |