Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10097452 | 0.95 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10250941 | 0.94 | SMN1; SMN2 (0.41) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL13151775 | 0.93 | ALDH1A1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10249577 | 0.93 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10097557 | 0.91 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10097413 | 0.91 | NPC1 (0.39) | ALDH1A1NPC1RAB9AHPGDCRHBP | |
| SCHEMBL13151832 | 0.91 | KCNQ2 (0.40) | ALDH1A1NPC1RAB9AHPGDCRHBP | |
| SCHEMBL10097430 | 0.90 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL13151852 | 0.90 | LMNA (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10097463 | 0.90 | MAPT (0.45) | NPC1RAB9ASMN1; SMN2PLA2G2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009142-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009142-A1 | METHODS FOR TREATING HEPATITIS C | OAT, HAVCR2, HCCS | ALDH1A1 591/4885NPC1 297/4885RAB9A 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.