SCHEMBL1025152

SCHEMBL1025152

Nc1cc2c(c3ccccc13)C(=O)OC2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 1/20 0.43
HPRT1 P00492 1/20 0.37
ADORA2A P29274 2/20 0.36
FGR P09769 1/20 0.36
PIM1 P11309 1/20 0.36
MAOA P21397 1/20 0.36
CSNK1A1 P48729 1/20 0.36
CSNK1D P48730 1/20 0.36
DYRK1A Q13627 1/20 0.36
HIPK2 Q9H2X6 1/20 0.36
CSNK1G1 Q9HCP0 1/20 0.36
PKM P14618 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153260 0.79 GFER (0.42) NQO1TDP1ALOX15PKMKMT2A
SCHEMBL212888 0.77 TYMS (0.46) TDP1ALOX15PKMKMT2ASMN1; SMN2
SCHEMBL29501815 0.77 ALOX15 (0.43) TDP1ALOX15KMT2ASMN1; SMN2ALOX5
SCHEMBL31634605 0.77 CYP1A2 (0.44) TDP1ALOX15MAOAKMT2ASMN1; SMN2
SCHEMBL9166710 0.77 CA12 (0.47) TDP1ALOX15PIM1MAOAKMT2A
SCHEMBL1518035 0.77 ALOX15 (0.43) TDP1ALOX15KMT2ASMN1; SMN2ALOX5
SCHEMBL4959186 0.77 ALOX15 (0.43) TDP1ALOX15HPRT1NPC1RAB9A
SCHEMBL4960375 0.77 ALOX15 (0.43) TDP1ALOX15SMN1; SMN2MAPK1ALOX5
SCHEMBL12447848 0.74 ALOX15 (0.40) TDP1ALOX15NPC1RAB9ASMN1; SMN2
SCHEMBL7541755 0.74 TDP1 (0.40) TDP1ALOX15MAOAKMT2AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1204000-B1 Photosensitive lithographic printing plate FUJIFILM CORP (JP) 2011-01-12 EP disclosed
EP-1216830-B1 Negative photo- or heat- sensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2007-03-07 EP disclosed
CN-1228689-C Negative light-sensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2005-11-23 CN disclosed
US-6794116-B2 ADDITION POLYMER; PHOTOPOLYMERIZATION FUJI PHOTO FILM CO., LTD. (JP) 2004-09-21 US disclosed
US-6777155-B2 PHOTOSENSITIVE LAYER INCLUDES A POLYURETHANE RESIN BINDER COMPRISING AN ALIPHATIC CYCLIC STRUCTURE WHICH HAS A CARBOXYL GROUP AS A SUBSTITUENT FUJI PHOTO FILM CO., LTD. (JP) 2004-08-17 US disclosed
CN-1373395-A Negative light-sensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2002-10-09 CN disclosed
US-20020142249-A1 Addition polymer; photopolymerization FUJIFILM CORPORATION (JP) 2002-10-03 US disclosed
US-20020136987-A1 Photosensitive layer includes a polyurethane resin binder comprising an aliphatic cyclic structure which has a carboxyl group as a substituent FUJIFILM CORPORATION (JP) 2002-09-26 US disclosed
EP-1216830-A2 Negative photo- or heat- sensitive lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2002-06-26 EP disclosed
EP-1204000-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
US-4052378-A RED PIGMENT OBTAINED BY COUPLING DIAZOTIZED 4-AMINONAPHTHALIMIDE WITH 2,6-DIHYDROXY-3-CYANO-4-METHYLPYRIDINE BASF FARBEN + FASERN AG (DT) 1977-10-04 US disclosed