SCHEMBL7541755

SCHEMBL7541755

O=Cc1cc2c(c3ccccc13)C(=O)OC2=O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
ALOX15 P16050 1/20 0.40
MCL1 Q07820 1/20 0.39
PTPN1 P18031 8/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.37
POLB P06746 2/20 0.36
PTPN2 P17706 2/20 0.36
PRKDC P78527 1/20 0.35
CYP2A6 P11509 2/20 0.34
IMPDH2 P12268 2/20 0.34
ALOX5 P09917 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TYMS P04818 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28442695 0.84 ALOX15 (0.39) TDP1ALOX15ALOX5ALDH1A1TYMS
SCHEMBL31634605 0.78 CYP1A2 (0.44) TDP1ALOX15MAOAMEN1KMT2A
SCHEMBL212888 0.74 TYMS (0.46) TDP1ALOX15MEN1KMT2ALMNA
SCHEMBL4959186 0.74 ALOX15 (0.43) TDP1ALOX15LMNAPRKDCALOX5
SCHEMBL1025152 0.74 NQO1 (0.44) TDP1ALOX15MAOAMEN1KMT2A
SCHEMBL29501815 0.74 ALOX15 (0.43) TDP1ALOX15MEN1KMT2AALOX5
SCHEMBL9166710 0.74 CA12 (0.47) TDP1ALOX15MCL1MAOAMEN1
SCHEMBL4960375 0.74 ALOX15 (0.43) TDP1ALOX15ALOX5ALDH1A1TYMS
SCHEMBL1518035 0.74 ALOX15 (0.43) TDP1ALOX15MEN1KMT2AALOX5
SCHEMBL8637609 0.74 PARP1 (0.42) TDP1MCL1MAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 TDP1 3063/4885ALOX15 1802/4885MCL1 3029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.