SCHEMBL212888

SCHEMBL212888

O=C1OC(=O)c2c1cc(Cl)c1ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.46
ALOX15 P16050 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP1A2 P05177 4/20 0.39
CYP2A6 P11509 2/20 0.39
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
TSHR P16473 1/20 0.37
ALOX5 P09917 1/20 0.35
NPSR1 Q6W5P4 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11423045 0.81 TYMS (0.51) TYMSALOX15TDP1CYP1A2CYP2A6
SCHEMBL4960390 0.79 TYMS (0.58) TYMSALOX15TDP1CYP1A2CYP2A6
SCHEMBL18016203 0.77 PON1 (0.40) TYMSALDH1A1MAPTNFKB1CYP2C19
SCHEMBL31634605 0.77 CYP1A2 (0.44) ALOX15TDP1CYP1A2CYP2A6ALDH1A1
SCHEMBL1518035 0.77 ALOX15 (0.43) TYMSALOX15TDP1CYP1A2ALDH1A1
SCHEMBL4960375 0.77 ALOX15 (0.43) TYMSALOX15TDP1ALDH1A1HPGD
SCHEMBL29501815 0.77 ALOX15 (0.43) TYMSALOX15TDP1CYP1A2ALDH1A1
SCHEMBL4959186 0.77 ALOX15 (0.43) TYMSALOX15TDP1CYP1A2ALDH1A1
SCHEMBL9166710 0.77 CA12 (0.47) ALOX15TDP1ALDH1A1MEN1KMT2A
SCHEMBL1025152 0.77 NQO1 (0.44) TYMSALOX15TDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015438-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-15 US disclosed
US-12297316-B2 Orthodontic articles prepared using a polycarbonate diol, polymerizable compositions, and methods of making the articles SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-13 US disclosed
US-20240270893-A1 ORTHODONTIC ARTICLES PREPARED USING A POLYCARBONATE DIOL, POLYMERIZABLE COMPOSITIONS, AND METHODS OF MAKING THE ARTICLES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-08-15 US disclosed
CN-118355090-A Boron-containing cyclic light-emitting compound and color conversion film containing same 日东电工株式会社 2024-07-16 CN disclosed
WO-2024137915-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (US) 2024-06-27 WO disclosed
CN-118251979-A Wavelength conversion film and display device including the same 日东电工株式会社 2024-06-25 CN disclosed
WO-2024119026-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2024-06-06 WO disclosed
WO-2024081802-A1 WAVELENGTH CONVERSION FILM AND DISPLAY DEVICE INCLUDING THE SAME NITTO DENKO CORPORATION (US) 2024-04-18 WO disclosed
US-11945900-B2 Orthodontic articles prepared using a polycarbonate diol, polymerizable compositions, and methods of making the articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-02 US disclosed
CN-117396580-A Boron-containing cyclic light-emitting compound and color conversion film comprising the same 日东电工株式会社 2024-01-12 CN disclosed
US-4485160-A INORGANIC PARTICLES, SENSITIZING DYES AND ELECTRON-ATTRACTING COMPOUNDS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1984-11-27 US disclosed
EP-0099552-A2 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1984-02-01 EP disclosed
US-4396696-A Electrophotographic plate having azo compound photosensitive layer MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-08-02 US disclosed
US-4367273-A Electrophotographic plate comprising a conductive substrate and a photosensitive layer containing an organic photoconductor layer composed of a hydrazone compound MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-01-04 US disclosed
EP-0063387-A1 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1982-10-27 EP disclosed
US-4278747-A Electrophotographic plate comprising a conductive substrate and a photosensitive layer containing an organic photoconductor layer composed of a hydrazone compound MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1981-07-14 US disclosed
US-4212813-A OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1980-07-15 US disclosed
US-4172202-A Process for the preparation of 4-amino-1,8-naphthalimides HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-23 US disclosed
US-4081446-A DEHALOGENATION, AMMONIATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-28 US disclosed
US-4033986-A Process for the preparation of 4-bromo-1,8-naphthalic acid anhydride AMERICAN HOECHST CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015438-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods HTR3D, EIF3D, MYD88 TYMS 2137/4885ALOX15 2429/4885TDP1 697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.