Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644039 | 0.94 | BRD4 (0.41) | HIF1ABRD4SLC7A5RXRARXRB | |
| SCHEMBL10253009 | 0.82 | HIF1A (0.39) | HIF1ABRD4SLC7A5RXRARXRB | |
| SCHEMBL10253055 | 0.81 | HPGD (0.41) | BRD4SLC7A5RXRARXRBRXRG | |
| SCHEMBL10252815 | 0.79 | L3MBTL1 (0.41) | SLC7A5RXRARXRBRXRGFFAR4 | |
| SCHEMBL643639 | 0.78 | HIF1A (0.41) | HIF1ABRD4SLC7A5RXRARXRB | |
| SCHEMBL10253000 | 0.77 | SMPD1 (0.44) | SLC7A5RXRARXRBRXRGFFAR4 | |
| SCHEMBL642663 | 0.76 | HPGD (0.44) | BRD4SLC7A5RXRARXRBRXRG | |
| SCHEMBL2664896 | 0.76 | ESR1 (0.36) | HIF1ARXRA | |
| SCHEMBL9204010 | 0.74 | RXRA (0.48) | SLC7A5RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL644658 | 0.74 | SMPD1 (0.48) | BRD4SLC7A5RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119624-B2 | Fused phenyl amido heterocyclic compounds | PFIZER INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110039821-A1 | Fused Phenyl Amido Heterocyclic Compounds | PFIZER INC | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039821-A1 | Fused Phenyl Amido Heterocyclic Compounds | GCK, GCKR, HK1 | HIF1A 595/4885BRD4 1411/4885SLC7A5 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.