Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258937 | 0.84 | KMT2A (0.53) | KMT2AMEN1TP53MAPTSMN1; SMN2 | |
| SCHEMBL28451725 | 0.81 | KMT2A (0.50) | KMT2AMEN1TP53MAPTSMN1; SMN2 | |
| SCHEMBL28448945 | 0.79 | KMT2A (0.48) | KMT2AMEN1TP53MAPTSMN1; SMN2 | |
| SCHEMBL10250839 | 0.79 | KMT2A (0.56) | KMT2AMEN1TP53MAPTSMN1; SMN2 | |
| SCHEMBL15605486 | 0.73 | SMYD3 (0.39) | KMT2ATP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10257491 | 0.73 | DCPS (0.46) | — | |
| SCHEMBL10259580 | 0.70 | SSTR4 (0.32) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10267233 | 0.69 | SCD (0.37) | KMT2AMEN1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL19901686 | 0.69 | CCR5 (0.36) | KMT2ATP53MAPTNPC1RAB9A | |
| SCHEMBL621093 | 0.68 | SSTR4 (0.40) | KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |