Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CLPP | Q16740 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750026 | 1.00 | METAP2 (0.39) | METAP2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL749159 | 1.00 | METAP2 (0.39) | METAP2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL747606 | 0.97 | ALDH1A1 (0.38) | METAP2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL749169 | 0.97 | ALDH1A1 (0.38) | METAP2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL762965 | 0.94 | CLPP (0.38) | ALDH1A1KMT2ACYP3A4CLPP | |
| SCHEMBL747474 | 0.94 | CLPP (0.38) | ALDH1A1KMT2ACYP3A4CLPP | |
| SCHEMBL747186 | 0.93 | METAP2 (0.40) | METAP2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL746174 | 0.93 | METAP2 (0.40) | METAP2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL746033 | 0.92 | ALDH1A1 (0.39) | METAP2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL749196 | 0.92 | ALDH1A1 (0.39) | METAP2ALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101751-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-24 | — | — | US | disclosed |
| US-8101751-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-24 | — | — | US | disclosed |