Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12470770 | 0.88 | ALOX5 (0.57) | CYP3A4ALOX5MAOBPDGFRBPDGFRA | |
| SCHEMBL16047250 | 0.83 | MAOB (0.54) | CYP3A4ALOX5MAOBPDGFRBPDGFRA | |
| SCHEMBL30864290 | 0.82 | PDGFRB (0.60) | CYP3A4ALOX5MAOBPDGFRBPDGFRA | |
| SCHEMBL6966030 | 0.82 | CYP3A4 (0.62) | CYP3A4ALOX5MAOBPDGFRBPDGFRA | |
| SCHEMBL18571362 | 0.81 | CYP3A4 (0.61) | CYP3A4ALOX5MAOBPDGFRBPDGFRA | |
| SCHEMBL29576561 | 0.81 | ALOX5 (0.73) | CYP3A4ALOX5MAOBNPC1RAB9A | |
| SCHEMBL2636350 | 0.81 | ALOX5 (0.73) | CYP3A4ALOX5MAOBNPC1RAB9A | |
| SCHEMBL18571363 | 0.80 | CYP3A4 (0.59) | CYP3A4ALOX5MAOBPDGFRBPDGFRA | |
| SCHEMBL17316167 | 0.79 | HPGDS (0.62) | CYP3A4ALOX5MAOBPDGFRBPDGFRA | |
| SCHEMBL18572104 | 0.78 | MAPT (0.45) | CYP3A4MAOBPDGFRBPDGFRANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306737-A | Benzo heterocyclic compound, pharmaceutically acceptable salt or stereoisomer thereof, and preparation method and application thereof | 江苏集萃分子工程研究院有限公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2020063854-A1 | QUINOLINE-BASED DERIVATIVES AS VAP-1 INHIBITORS | 南京明德新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |
| US-8212011-B2 | Novobiocin analogues | UNIVERSITY OF KANSAS (US) | 2012-07-03 | — | — | US | disclosed |
| US-8212012-B2 | Novobiocin analogues having modified sugar moieties | UNIVERSITY OF KANSAS (US) | 2012-07-03 | — | — | US | disclosed |
| US-20090187014-A1 | Novobiocin Analogues | UNIVERSITY OF KANSAS | 2009-07-23 | — | — | US | disclosed |
| US-20090163709-A1 | Novobiocin Analogues Having Modified Sugar Moieties | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163709-A1 | Novobiocin Analogues Having Modified Sugar Moieties | HSP90AB1, HSP90B1, HSP90AB2P | CYP3A4 4380/4885ALOX5 4071/4885MAOB 3684/4885 |
| US-20090187014-A1 | Novobiocin Analogues | SSB, SSBP1, BTD | CYP3A4 4317/4885ALOX5 2130/4885MAOB 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.