Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 5/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434950 | 0.90 | MAPT (0.47) | FFAR1HPGDFFAR4NR1H4ALDH1A1 | |
| SCHEMBL433419 | 0.85 | FFAR1 (0.52) | FFAR1HPGDFFAR4ACACBNR1H4 | |
| SCHEMBL433418 | 0.85 | FFAR1 (0.52) | FFAR1HPGDFFAR4ACACBNR1H4 | |
| SCHEMBL197785 | 0.76 | ALDH1A1 (0.51) | FFAR1HPGDACACBNR1H4ACACA | |
| SCHEMBL3091164 | 0.76 | FFAR1 (0.68) | FFAR1FFAR4NR1H4LTA4HALDH1A1 | |
| SCHEMBL18469380 | 0.75 | MAPT (0.61) | LTA4HALDH1A1MAPTGAARAB9A | |
| SCHEMBL2773462 | 0.74 | FFAR1 (0.68) | FFAR1FFAR4NR1H4ALDH1A1CYP4F2 | |
| SCHEMBL8550447 | 0.74 | ABCB1 (0.57) | FFAR1HPGDFFAR4LTA4HALDH1A1 | |
| SCHEMBL434809 | 0.73 | FFAR1 (0.59) | FFAR1FFAR4 | |
| SCHEMBL434810 | 0.73 | FFAR1 (0.59) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |