SCHEMBL8550447

SCHEMBL8550447

CCOC(=O)COc1ccc(CCC(=O)OCc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.57
FFAR1 O14842 1/20 0.55
FFAR4 Q5NUL3 1/20 0.55
GAA P10253 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
CYP4F2 P78329 1/20 0.54
CYP4A11 Q02928 1/20 0.54
TDP1 Q9NUW8 1/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TP53 P04637 1/20 0.51
HSD17B10 Q99714 1/20 0.51
LTA4H P09960 5/20 0.51
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626583 0.96 ABCB1 (0.54) ABCB1FFAR1FFAR4GAAMEN1
SCHEMBL8625075 0.91 ALDH1A1 (0.59) ABCB1GAAMAPTHPGDKDM4E
SCHEMBL3091164 0.89 FFAR1 (0.68) FFAR1FFAR4CYP4F2CYP4A11TDP1
SCHEMBL8625079 0.87 KMT2A (0.60) ABCB1GAAMEN1KMT2ACYP4F2
SCHEMBL782070 0.87 FFAR1 (0.64) FFAR1FFAR4GAAMEN1KMT2A
SCHEMBL2773462 0.85 FFAR1 (0.68) FFAR1FFAR4CYP4F2CYP4A11TDP1
SCHEMBL783355 0.85 FFAR1 (0.52) FFAR1FFAR4GAAMEN1KMT2A
SCHEMBL6187602 0.85 NR1H4 (0.64) GAAMEN1KMT2AMAPTHPGD
SCHEMBL7276062 0.85 FFAR1 (0.74) FFAR1FFAR4TDP1LTA4H
SCHEMBL14395504 0.84 TDP1 (0.62) FFAR1FFAR4MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817677-A ANTITHROMBOSIS AGENTS DR. KARL THOMAE GMBH (DE) 1998-10-06 US disclosed
EP-0858457-A1 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM Dr. Karl Thomae GmbH (DE) 1998-08-19 EP disclosed
WO-1997015567-A1 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM DR. KARL THOMAE GMBH (DE) 1997-05-01 WO disclosed