SCHEMBL102630

SCHEMBL102630

O=[N+]([O-])C=Cc1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 13/20 1.00
EGFR P00533 2/20 0.64
ALDH1A1 P00352 3/20 0.58
LMNA P02545 3/20 0.58
MAPT P10636 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
VCP P55072 1/20 0.58
TLR4 O00206 1/20 0.55
TLR2 O60603 1/20 0.55
ABL1 P00519 1/20 0.53
ABL2 P42684 1/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
S1PR4 O95977 1/20 0.51
HSP90AA1 P07900 1/20 0.51
HPGD P15428 1/20 0.51
S1PR1 P21453 1/20 0.51
MAPK1 P28482 1/20 0.51
CCR6 P51684 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102629 1.00 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL12635599 0.89 FBP1 (0.79) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL6910815 0.89 FBP1 (0.78) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL6910818 0.89 FBP1 (0.78) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL2077034 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL2285894 0.78 FBP1 (0.67) FBP1EGFRALDH1A1MAPTSMN1; SMN2
SCHEMBL2077031 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL15730011 0.78 FBP1 (0.64) FBP1ALDH1A1MAPT
SCHEMBL366121 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL219464 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136761-A Method for synthesizing pyrrole compound 南京理工大学 2025-06-13 CN claimed
CN-115521208-B Novel coronavirus 3CL protease inhibitor and application 天津科技大学 2023-09-01 CN claimed
CN-113943242-B Preparation method of polysubstituted pyrrole compound 浙江工业大学 2023-08-15 CN claimed
CN-115521208-A Novel coronavirus 3CL protease inhibitor and application 天津科技大学 2022-12-27 CN claimed
CN-111116613-B Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof 湘潭大学 2021-04-23 CN claimed
CN-104277072-B A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) 2016-04-13 CN claimed
EP-2982368-A1 Small molecule compounds displacing focal adhesion core components Universität Konstanz (DE) 2016-02-10 EP claimed
CN-104277072-A Method for preparing (E)-2-aryl vinyl phosphonate derivatives CHINASUN SPECIALTY PRODUCTS CO LTD 2015-01-14 CN claimed
US-7132219-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2006-11-07 US claimed
EP-1397260-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2006-03-08 EP claimed
EP-1397260-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2004-03-17 EP claimed
US-20030219541-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-11-27 US claimed
US-20030064608-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition SABNIS RAM W (US) 2003-04-03 US claimed
US-20030054117-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-03-20 US claimed
WO-2002062593-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2002-08-15 WO claimed
EP-4651954-A1 INHIBITORS OF MPTP NRG Therapeutics LTD (GB) 2025-11-26 EP disclosed
EP-4627896-A2 3D/2D PEROVSKITE SOLAR CELLS ODTÜ-GÜNAM (TR) 2025-10-08 EP disclosed
EP-0138030-B1 PHENYLETHYLAMINE DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1987-09-30 EP disclosed
US-4656298-A MUSCLE RELAXANTS, STIMULANTS, ANALGESICS, ANTICONVULSANTS, ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1987-04-07 US disclosed
EP-0138030-A2 Phenylethylamine derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-04-24 EP disclosed