Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 12/20 | 0.79 |
| ▸ | TLR4 | O00206 | 4/20 | 0.73 |
| ▸ | TLR2 | O60603 | 4/20 | 0.73 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102629 | 0.89 | FBP1 (1.00) | FBP1TLR4TLR2EGFRKMT2A | |
| SCHEMBL102630 | 0.89 | FBP1 (1.00) | FBP1TLR4TLR2EGFRKMT2A | |
| SCHEMBL510018 | 0.84 | TLR4 (1.00) | FBP1TLR4TLR2EGFRMAOA | |
| SCHEMBL510019 | 0.84 | TLR4 (1.00) | FBP1TLR4TLR2EGFRMAOA | |
| SCHEMBL4905578 | 0.82 | FBP1 (0.81) | FBP1TLR4TLR2EGFRMAOA | |
| SCHEMBL4905572 | 0.82 | FBP1 (0.81) | FBP1TLR4TLR2EGFRMAOA | |
| SCHEMBL21483129 | 0.81 | TLR4 (0.65) | FBP1TLR4TLR2EGFRMAOA | |
| SCHEMBL18533681 | 0.80 | FBP1 (0.68) | FBP1TLR4TLR2EGFRKMT2A | |
| SCHEMBL10031850 | 0.79 | NFE2L2 (0.68) | — | |
| SCHEMBL6910818 | 0.79 | FBP1 (0.78) | FBP1TLR4TLR2EGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |