SCHEMBL102629

SCHEMBL102629

O=[N+]([O-])/C=C/c1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 13/20 1.00
EGFR P00533 2/20 0.64
ALDH1A1 P00352 3/20 0.58
LMNA P02545 3/20 0.58
MAPT P10636 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
VCP P55072 1/20 0.58
TLR4 O00206 1/20 0.55
TLR2 O60603 1/20 0.55
ABL1 P00519 1/20 0.53
ABL2 P42684 1/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
S1PR4 O95977 1/20 0.51
HSP90AA1 P07900 1/20 0.51
HPGD P15428 1/20 0.51
S1PR1 P21453 1/20 0.51
MAPK1 P28482 1/20 0.51
CCR6 P51684 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102630 1.00 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL12635599 0.89 FBP1 (0.79) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL6910815 0.89 FBP1 (0.78) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL6910818 0.89 FBP1 (0.78) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL2077034 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL2285894 0.78 FBP1 (0.67) FBP1EGFRALDH1A1MAPTSMN1; SMN2
SCHEMBL2077031 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL15730011 0.78 FBP1 (0.64) FBP1ALDH1A1MAPT
SCHEMBL366121 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL219464 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119678922-A Application of nitrostyrenes compound in preventing, controlling or resisting plant pathogenic nematodes and preparation thereof 广西田园生化股份有限公司 2025-03-25 CN claimed
CN-118844436-A Application of nitrostyrene compound in preventing and treating plant diseases and food-borne pathogenic bacteria 广西田园生化股份有限公司 2024-10-29 CN claimed
EP-2982368-A1 Small molecule compounds displacing focal adhesion core components Universität Konstanz (DE) 2016-02-10 EP claimed
US-7132219-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2006-11-07 US claimed
EP-1397260-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2006-03-08 EP claimed
EP-1397260-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2004-03-17 EP claimed
US-20030219541-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-11-27 US claimed
US-20030064608-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition SABNIS RAM W (US) 2003-04-03 US claimed
US-20030054117-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-03-20 US claimed
WO-2002062593-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2002-08-15 WO claimed
EP-4651954-A1 INHIBITORS OF MPTP NRG Therapeutics LTD (GB) 2025-11-26 EP disclosed
CN-119678922-A Application of nitrostyrenes compound in preventing, controlling or resisting plant pathogenic nematodes and preparation thereof 广西田园生化股份有限公司 2025-03-25 CN disclosed
CN-119678922-A Application of nitrostyrenes compound in preventing, controlling or resisting plant pathogenic nematodes and preparation thereof 广西田园生化股份有限公司 2025-03-25 CN disclosed
US-12162820-B2 Peripheral alkyl and alkenyl chains extended benzene derivatives and pharmaceutical composition including the same TAIWANJ PHARMACEUTICALS CO., LTD. (TW) 2024-12-10 US disclosed
CN-118844436-A Application of nitrostyrene compound in preventing and treating plant diseases and food-borne pathogenic bacteria 广西田园生化股份有限公司 2024-10-29 CN disclosed
US-5004826-A Chemical Intermediates For Muscle Relaxants, Muscle Stimulants, Analgesics, Anticonvulsants, Antidepressants, Nootropics, And Drugs For Reducing Drug Withdrawal Symptoms CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
EP-0181833-B1 SUBSTITUTED PROPANE-PHOSPHONOUS ACID COMPOUNDS CIBA-GEIGY AG (CH) 1990-05-02 EP disclosed
US-4908465-A Ethyl phenyl-3-nitropropyl(diethoxymethyl)phosphinate derivatives CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed
US-4772738-A MUSCLE RELAXANTS, ANALGESICS, ANTICONVULSANTS, ANTIDEPRESSANT CIBA-GEIGY CORPORATION (US) 1988-09-20 US disclosed
US-4656298-A MUSCLE RELAXANTS, STIMULANTS, ANALGESICS, ANTICONVULSANTS, ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1987-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162820-B2 Peripheral alkyl and alkenyl chains extended benzene derivatives and pharmaceutical composition including the same AADAC, ENPP2, ATXN10 FBP1 431/4885EGFR 3281/4885ALDH1A1 1691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.