Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.38 |
| ▸ | PPARA | Q07869 | 16/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180739 | 0.89 | ELANE (0.43) | PPARGPPARAELANE | |
| SCHEMBL2736910 | 0.79 | ELANE (0.49) | PPARAELANE | |
| SCHEMBL6184013 | 0.76 | ELANE (0.46) | PPARAELANE | |
| SCHEMBL13053746 | 0.73 | ALDH1A1 (0.44) | PPARGPPARA | |
| SCHEMBL13053751 | 0.71 | CTRB1 (0.38) | PPARGPPARAELANE | |
| SCHEMBL12094474 | 0.71 | ACACB (0.53) | PPARAELANE | |
| SCHEMBL6183996 | 0.71 | RIPK1 (0.53) | PPARAELANE | |
| SCHEMBL2737051 | 0.70 | ELANE (0.40) | PPARAELANE | |
| SCHEMBL12092652 | 0.70 | ACACB (0.55) | PPARAELANE | |
| SCHEMBL10257325 | 0.70 | ACACB (0.49) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404890-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-11 | — | — | EP | disclosed |