Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374023 | 0.84 | DRD2 (0.37) | PDE4D | |
| SCHEMBL8040790 | 0.84 | DRD2 (0.37) | PDE4D | |
| SCHEMBL12921600 | 0.82 | KMT2A (0.33) | PDE4D | |
| SCHEMBL373484 | 0.82 | KCNH2 (0.34) | — | |
| SCHEMBL15088438 | 0.82 | KCNH2 (0.34) | — | |
| SCHEMBL186820 | 0.82 | SRD5A1 (0.43) | PDE4D | |
| SCHEMBL12210438 | 0.79 | CHIT1 (0.35) | PDE4D | |
| SCHEMBL12921335 | 0.78 | PDE4D (0.32) | PDE4D | |
| SCHEMBL12921339 | 0.76 | GAA (0.34) | — | |
| SCHEMBL15976857 | 0.75 | CHIT1 (0.32) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215092-B1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |