Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 2/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186796 | 0.93 | PDE4D (0.37) | CHIT1CHIAPDE4DMMP2MMP9 | |
| SCHEMBL15976857 | 0.93 | CHIT1 (0.32) | CHIT1CHIAPDE4DSCN9ADRD2 | |
| SCHEMBL15088377 | 0.88 | CHIT1 (0.35) | CHIT1CHIASCN9ADRD2HTR3A | |
| SCHEMBL12921440 | 0.88 | CHIT1 (0.35) | CHIT1CHIASCN9ADRD2HTR3A | |
| SCHEMBL972213 | 0.88 | CHIT1 (0.35) | CHIT1CHIASCN9ADRD2HTR3A | |
| SCHEMBL15800089 | 0.88 | CHIT1 (0.35) | CHIT1CHIASCN9ADRD2HTR3A | |
| SCHEMBL15088390 | 0.88 | CHIT1 (0.35) | CHIT1CHIASCN9ADRD2HTR3A | |
| SCHEMBL12208780 | 0.88 | CHIT1 (0.35) | CHIT1CHIASCN9ADRD2HTR3A | |
| SCHEMBL186820 | 0.87 | SRD5A1 (0.43) | CHIT1CHIAPDE4DSCN9ADRD2 | |
| SCHEMBL8064967 | 0.86 | DRD2 (0.39) | CHIT1CHIASCN9ADRD2CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610258-B1 | Substituted piperidino dihydrothieno pyrimidines | BOEHRINGER INGELHEIM INT (DE) | 2014-08-27 | — | — | EP | disclosed |
| EP-2610258-A1 | Substituted piperidino dihydrothieno pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-03 | — | — | EP | disclosed |
| EP-2380891-A1 | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |