Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MTOR | P42345 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | HBB | P68871 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | HINT1 | P49773 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485203 | 1.00 | DNMT1 (0.57) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL10260614 | 1.00 | DNMT1 (0.57) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL10260271 | 0.88 | LMNA (0.43) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL19506684 | 0.85 | LMNA (0.51) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL10024704 | 0.83 | LMNA (0.52) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL14549613 | 0.83 | LMNA (0.52) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL13954141 | 0.83 | DNMT1 (0.79) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL12378332 | 0.83 | DNMT1 (0.79) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL17565536 | 0.83 | DNMT1 (0.79) | DNMT1LMNAMTORTP53GMNN | |
| SCHEMBL13954249 | 0.83 | DNMT1 (0.79) | DNMT1LMNAMTORTP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212021-B2 | Process for making 5-azacytosine nucleosides and their derivatives | SCINOPHARM TAIWAN, LTD. (TW) | 2012-07-03 | — | — | US | disclosed |
| US-20100036112-A1 | Process for Making 5-Azacytosine Nucleosides and Their Derivatives | SCINOPHARM TAIWAN LTD. | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036112-A1 | Process for Making 5-Azacytosine Nucleosides and Their Derivatives | DCTD, DUT, DPYD | DNMT1 14/4885LMNA 2350/4885MTOR 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.