Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10658292 | 0.81 | PTPN11 (0.58) | TSHRALDH1A1HSD17B10PTPN11KMT2A | |
| SCHEMBL10269054 | 0.80 | KDM4E (0.45) | ALDH1A1PTPN11LTA4HNR5A1RAB9A | |
| SCHEMBL10063478 | 0.79 | MAOB (0.54) | ALDH1A1LTA4HNR5A1RAB9AGAA | |
| SCHEMBL4257305 | 0.78 | ALDH1A1 (0.56) | TSHRALDH1A1HSD17B10PTPN11CYP1A2 | |
| SCHEMBL22281530 | 0.78 | NOS2 (0.54) | ALDH1A1RAB9AGAAMAPTNPC1 | |
| SCHEMBL10655121 | 0.77 | PTPN11 (0.65) | TSHRPTPN11 | |
| SCHEMBL30646245 | 0.77 | TSHR (0.53) | TSHRLTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11655575 | 0.77 | TSHR (0.53) | TSHRLTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13303355 | 0.76 | LTA4H (0.55) | TSHRALDH1A1LTA4HCYP1A2CYP2C9 | |
| SCHEMBL2154783 | 0.74 | MAPT (0.50) | ALDH1A1HSD17B10MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053148-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053148-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, FABP1, EIF2AK2 | TSHR 4587/4885ALDH1A1 2132/4885HSD17B10 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.