SCHEMBL10270300

SCHEMBL10270300

CC=Cc1ccc(N=Nc2ccc(C(O)CC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
CYP2C9 P11712 2/20 0.36
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
PGR P06401 1/20 0.33
PTGS2 P35354 2/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
CNR2 P34972 1/20 0.33
PTGS1 P23219 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10270315 0.73 MEN1 (0.50) LMNACYP2C9ALDH1A1KDM4ETP53
SCHEMBL28684202 0.73 KDM4E (0.38) LMNACYP2C9ALDH1A1KDM4ETP53
SCHEMBL20852369 0.73 CYP3A4 (0.40) LMNACYP2C9ALDH1A1KDM4ETP53
SCHEMBL1607138 0.72 LMNA (0.75) LMNACYP2C9ALDH1A1KDM4ECYP3A4
SCHEMBL14946519 0.71 CYP4F2 (0.46) LMNACYP2C9ALDH1A1KDM4ETP53
SCHEMBL8383891 0.71 LMNA (0.56) LMNACYP2C9ALDH1A1KDM4ECYP3A4
SCHEMBL19981100 0.71 ALDH1A1 (0.52) LMNAALDH1A1KDM4ETP53CYP3A4
SCHEMBL14679821 0.71 ALDH1A1 (0.52) LMNAALDH1A1KDM4ETP53CYP3A4
SCHEMBL10216097 0.71 NFE2L2 (0.45) LMNACYP2C9ALDH1A1KDM4ETP53
SCHEMBL10216126 0.70 ALDH1A1 (0.52) LMNAALDH1A1KDM4ECYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120107530-A1 Printing paper for printing stereoscopic image, stereoscopic image printed matter, and method for providing stereoscopic image FUJIFILM CORPORATION (JP) 2012-05-03 US disclosed