Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197722 | 0.86 | LMNA (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6278089 | 0.86 | LMNA (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL29640598 | 0.86 | LMNA (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL4123718 | 0.86 | LMNA (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6975204 | 0.86 | LMNA (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL4127615 | 0.86 | LMNA (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL4123720 | 0.86 | LMNA (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6514954 | 0.77 | CHRNB2 (0.38) | MAPT | |
| SCHEMBL6514956 | 0.77 | CHRNB2 (0.38) | MAPT | |
| SCHEMBL4196392 | 0.77 | CHRNB2 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415764-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | Kowa Company, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |