Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127615 | 1.00 | LMNA (0.39) | LMNANPSR1MAPTHTTGFER | |
| SCHEMBL6278089 | 1.00 | LMNA (0.39) | LMNANPSR1MAPTHTTGFER | |
| SCHEMBL4123718 | 1.00 | LMNA (0.39) | LMNANPSR1MAPTHTTGFER | |
| SCHEMBL4123720 | 1.00 | LMNA (0.39) | LMNANPSR1MAPTHTTGFER | |
| SCHEMBL6975204 | 1.00 | LMNA (0.39) | LMNANPSR1MAPTHTTGFER | |
| SCHEMBL4197722 | 1.00 | LMNA (0.39) | LMNANPSR1MAPTHTTGFER | |
| SCHEMBL6584622 | 0.86 | GAA (0.44) | MAPTTSHRBRD4BRD2BRD3 | |
| SCHEMBL10270645 | 0.86 | MAPT (0.39) | NPSR1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL10270762 | 0.86 | MAPT (0.39) | LMNANPSR1MAPTHTTGFER | |
| SCHEMBL225369 | 0.83 | BRD4 (0.43) | LMNANPSR1MAPTHTTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229104-B | Method for synthesizing tetrahydroquinoline compound by catalyzing arylamine and alpha-keto ester with cyclopentadienyl titanium/Bronsted acid | 陕西师范大学 | 2022-06-07 | — | — | CN | disclosed |