Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197722 | 0.86 | LMNA (0.39) | MAPTMEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL6975204 | 0.86 | LMNA (0.39) | MAPTMEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL29640598 | 0.86 | LMNA (0.39) | MAPTMEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL4127615 | 0.86 | LMNA (0.39) | MAPTMEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL4123720 | 0.86 | LMNA (0.39) | MAPTMEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL4123718 | 0.86 | LMNA (0.39) | MAPTMEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL6278089 | 0.86 | LMNA (0.39) | MAPTMEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL6584622 | 0.81 | GAA (0.44) | MAPTKDM4EALDH1A1BRD4CREBBP | |
| SCHEMBL225370 | 0.79 | BRD4 (0.43) | MAPTKDM4EALDH1A1BRD4CREBBP | |
| SCHEMBL225369 | 0.79 | BRD4 (0.43) | MAPTKDM4EALDH1A1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415764-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | Kowa Company, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |