Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.38 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771688 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1LMNAPOLB | |
| SCHEMBL1507229 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1POLBCHRNB2 | |
| SCHEMBL3895000 | 0.89 | LMNA (0.47) | ALDH1A1KDM4ETDP1LMNAPOLB | |
| Sulfuric Acid SCHEMBL229799 | 0.88 | KDM4E (0.71) | ALDH1A1KDM4ETDP1POLBCHRNB2 | |
| SCHEMBL332134 | 0.86 | KDM4E (0.68) | ALDH1A1KDM4ETDP1POLBCHRNB2 | |
| Sulfuric Acid SCHEMBL7637635 | 0.86 | KDM4E (0.68) | ALDH1A1KDM4ETDP1POLBCHRNB2 | |
| Sulfuric Acid SCHEMBL2243812 | 0.86 | KDM4E (0.68) | ALDH1A1KDM4ETDP1POLBCHRNB2 | |
| Thiosulfuric Acid SCHEMBL8424190 | 0.85 | KDM4E (0.65) | ALDH1A1KDM4ETDP1POLBCHRNB2 | |
| Sulfuric Acid SCHEMBL229801 | 0.85 | KDM4E (0.65) | ALDH1A1KDM4ETDP1LMNAPOLB | |
| SCHEMBL330944 | 0.85 | KDM4E (0.65) | ALDH1A1KDM4ETDP1POLBCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185734-A1 | Method for reducing or avoiding alkali-aggregate reaction in set concrete | WACKER CHEMIE AG (DE) | 2022-06-16 | — | — | US | disclosed |
| EP-3947314-A1 | METHOD FOR REDUCING OR AVOIDING ALKALI-AGGREGATE REACTION IN SET CONCRETE | Wacker Chemie AG (DE) | 2022-02-09 | — | — | EP | disclosed |
| CN-113574031-A | Method for reducing or avoiding alkali-aggregate reactions in set concrete | 瓦克化学股份公司 | 2021-10-29 | — | — | CN | disclosed |
| US-10882960-B2 | Method for the hydrophobic impregnation of fired ceramic molded bodies | WACKER CHEMIE AG (DE) | 2021-01-05 | — | — | US | disclosed |
| WO-2020192916-A1 | METHOD FOR REDUCING OR AVOIDING ALKALI-AGGREGATE REACTION IN SET CONCRETE | WACKER CHEMIE AG (DE) | 2020-10-01 | — | — | WO | disclosed |
| EP-3619274-B1 | AQUEOUS DISPERSIONS OF ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2020-09-09 | — | — | EP | disclosed |
| EP-3619274-A1 | AQUEOUS DISPERSIONS OF ORGANOSILICON COMPOUNDS | Wacker Chemie AG (DE) | 2020-03-11 | — | — | EP | disclosed |
| US-10584244-B2 | Aqueous dispersions of organosilicon compounds | WACKER CHEMIE AG (DE) | 2020-03-10 | — | — | US | disclosed |
| EP-3452173-B1 | AQUEOUS EMULSIONS CONTAINING AMINO-FUNCTIONAL ORGANOPOLYSILOXANES AND NON-IONIC EMULSIFIERS | WACKER CHEMIE AG (DE) | 2019-10-23 | — | — | EP | disclosed |
| CN-107223151-B | Aqueous dispersions of organosilicon compounds | 瓦克化学股份公司 | 2019-07-05 | — | — | CN | disclosed |
| US-8907011-B2 | Aqueous dispersions of organosilicon compounds | WACKER CHEMIE AG (DE) | 2014-12-09 | — | — | US | disclosed |
| WO-2014019878-A1 | NON-FILM-FORMING FORMULATIONS BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2014-02-06 | — | — | WO | disclosed |
| US-20140020600-A1 | AQUEOUS DISPERSIONS OF ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2014-01-23 | — | — | US | disclosed |
| US-8449666-B2 | Aqueous dispersions of organosilicon compounds | WACKER CHEMIE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-2065431-B1 | Aqueous Dispersions of Organosilicon Compounds | WACKER CHEMIE AG (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-20090139434-A1 | AQUEOUS DISPERSIONS OF ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2009-06-04 | — | — | US | disclosed |
| EP-2065431-A1 | Aqueous Dispersions of Organosilicon Compounds | Wacker Chemie AG (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-1554327-B1 | CELLULAR POLYURETHANE ELASTOMERS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | BAYER MATERIALSCIENCE AG (DE) | 2008-03-26 | — | — | EP | disclosed |
| US-20040077740-A1 | Cellular polyurethane elastomers, a process for preparing these and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-22 | — | — | US | disclosed |
| US-4771066-A | 4-haloalkylthio-5-amino-1-arylpyrazoles, composition containing them, and insecticidal and acaricidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |