Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10273114 | 0.94 | ITGA4 (0.67) | ITGA4ITGB1 | |
| SCHEMBL85013 | 0.94 | ITGB1 (0.78) | ITGA4ITGB1 | |
| SCHEMBL91569 | 0.91 | ITGA4 (0.77) | ITGA4ITGB1 | |
| SCHEMBL10273120 | 0.90 | ITGA4 (0.71) | ITGA4ITGB1 | |
| SCHEMBL84892 | 0.90 | ITGA4 (0.67) | ITGA4ITGB1 | |
| SCHEMBL93087 | 0.89 | ITGA4 (0.70) | ITGA4ITGB1 | |
| SCHEMBL10273884 | 0.87 | ITGA4 (0.70) | ITGA4ITGB1 | |
| SCHEMBL85489 | 0.87 | ITGB1 (0.80) | ITGA4ITGB1 | |
| SCHEMBL10273108 | 0.87 | ITGA4 (0.73) | ITGA4ITGB1 | |
| SCHEMBL10273131 | 0.86 | ITGA4 (0.68) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157437-A1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157437-A1 | VLA-4 INHIBITORY DRUG | VCAM1, ITGB4, ITGA4 | ITGA4 3/4885ITGB1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.