Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978366 | 0.90 | — | — | |
| SCHEMBL28978364 | 0.90 | — | — | |
| SCHEMBL28978369 | 0.90 | — | — | |
| SCHEMBL31703376 | 0.87 | CTSS (0.38) | AAK1MMP13MEN1GAAKMT2A | |
| SCHEMBL1128243 | 0.87 | CTSS (0.38) | AAK1MMP13MEN1GAAKMT2A | |
| SCHEMBL67050 | 0.87 | CTSS (0.38) | AAK1MMP13MEN1GAAKMT2A | |
| SCHEMBL27645074 | 0.87 | CTSS (0.38) | AAK1MMP13MEN1GAAKMT2A | |
| SCHEMBL1486202 | 0.87 | CTSS (0.38) | AAK1MMP13MEN1GAAKMT2A | |
| SCHEMBL67051 | 0.87 | CTSS (0.38) | AAK1MMP13MEN1GAAKMT2A | |
| SCHEMBL15674524 | 0.84 | AAK1 (0.32) | AAK1MMP13MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |