⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978364 | 1.00 | — | — | |
| SCHEMBL28978369 | 1.00 | — | — | |
| SCHEMBL10273899 | 0.90 | AAK1 (0.32) | — | |
| SCHEMBL15697048 | 0.86 | — | — | |
| SCHEMBL15697059 | 0.84 | MMP13 (0.34) | — | |
| SCHEMBL28978374 | 0.80 | — | — | |
| SCHEMBL28978376 | 0.80 | — | — | |
| SCHEMBL28978367 | 0.80 | — | — | |
| SCHEMBL23110306 | 0.80 | POLB (0.40) | — | |
| SCHEMBL1486202 | 0.77 | CTSS (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761033-A | Medicament for radical therapy of refractory hereditary nephrotic Alport syndrome | 国立大学法人熊本大学 | 2022-07-15 | — | — | CN | disclosed |