Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366735 | 0.80 | HTT (0.48) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL367200 | 0.77 | KDM4E (0.55) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL366887 | 0.75 | KDM4E (0.56) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL364541 | 0.72 | KDM4E (1.00) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL365854 | 0.71 | KDM4E (0.55) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL364930 | 0.71 | MAPT (0.51) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL11300422 | 0.69 | PADI4 (0.55) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL365561 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL364760 | 0.68 | KDM4E (0.63) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL365621 | 0.68 | MAPT (0.53) | ALDH1A1MEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |