Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 6/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367568 | 0.81 | ALDH1A1 (0.44) | HTTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL367329 | 0.81 | BAZ2B (0.47) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL10274437 | 0.80 | ALDH1A1 (0.56) | HTTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL366875 | 0.79 | EGFR (0.42) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL366736 | 0.77 | ALDH1A1 (0.41) | HTTALDH1A1KMT2AMEN1GAA | |
| Potassium Ion SCHEMBL364866 | 0.77 | MAPT (0.40) | HTTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL365546 | 0.77 | KMT2A (0.64) | HTTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL364280 | 0.76 | MAPT (0.47) | HTTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL366441 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1GAACYP1A2 | |
| SCHEMBL364388 | 0.75 | ALDH1A1 (0.43) | HTTALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |