Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313476 | 0.79 | CRHR1 (0.39) | CRHR1MARS1 | |
| SCHEMBL10275442 | 0.76 | ARF6 (0.41) | CRHR1MARS1 | |
| SCHEMBL10275893 | 0.76 | CYP3A4 (0.41) | CRHR1 | |
| SCHEMBL10276296 | 0.75 | PSD (0.52) | CRHR1 | |
| SCHEMBL10275643 | 0.73 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL10275579 | 0.72 | MEN1 (0.37) | — | |
| SCHEMBL12826181 | 0.72 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL13515966 | 0.72 | MAPT (0.46) | CRHR1 | |
| SCHEMBL10275312 | 0.71 | CNR1 (0.41) | CRHR1 | |
| SCHEMBL10275805 | 0.70 | MEN1 (0.46) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | TYMP, TYMS, ADORA3 | CRHR1 1464/4885MARS1 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.