Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027996 | 1.00 | L3MBTL1 (0.50) | L3MBTL1LIPEPDE4DPDE4APDE4B | |
| SCHEMBL1030605 | 0.87 | PDE4D (0.43) | L3MBTL1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1030606 | 0.87 | PDE4D (0.43) | L3MBTL1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4880746 | 0.81 | PDE4D (0.52) | PDE4DPDE4APDE4BPDE4CCES2 | |
| SCHEMBL1032137 | 0.81 | PDE4D (0.52) | L3MBTL1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4880751 | 0.81 | PDE4D (0.52) | PDE4DPDE4APDE4BPDE4CCES2 | |
| SCHEMBL1032139 | 0.81 | PDE4D (0.52) | L3MBTL1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1031080 | 0.80 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CCES2 | |
| SCHEMBL1081987 | 0.80 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CCES2 | |
| SCHEMBL4881516 | 0.78 | ALDH1A1 (0.48) | L3MBTL1PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044023-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDYNYL ALKYLENE ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMA SPA (IT) | 2011-01-19 | — | — | EP | disclosed |