Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881513 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1USP2NPSR1 | |
| SCHEMBL1032139 | 0.85 | PDE4D (0.52) | ALDH1A1L3MBTL1USP2NPSR1PDE4D | |
| SCHEMBL1032137 | 0.85 | PDE4D (0.52) | ALDH1A1L3MBTL1USP2NPSR1PDE4D | |
| SCHEMBL4880751 | 0.85 | PDE4D (0.52) | ALDH1A1LMNAPDE4DMEN1HPGD | |
| SCHEMBL4880746 | 0.85 | PDE4D (0.52) | ALDH1A1LMNAPDE4DMEN1HPGD | |
| SCHEMBL1027709 | 0.82 | PDE4D (0.54) | PDE4DMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1027708 | 0.82 | PDE4D (0.54) | PDE4DMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1027997 | 0.78 | L3MBTL1 (0.50) | LMNAL3MBTL1PDE4DPDE4APDE4B | |
| SCHEMBL1027996 | 0.78 | L3MBTL1 (0.50) | LMNAL3MBTL1PDE4DPDE4APDE4B | |
| SCHEMBL1081987 | 0.78 | PDE4D (0.46) | ALDH1A1PDE4DMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015226-A1 | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A.. | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015226-A1 | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors | PDE4A, PDE4B, PDE12 | ALDH1A1 57/4885LMNA 1507/4885L3MBTL1 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.