Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 5/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 5/20 | 0.33 |
| ▸ | SLC2A2 | P11168 | 2/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10279970 | 0.92 | DGAT2 (0.37) | SLC2A1SLC2A3SLC2A4SLC2A2DGAT2 | |
| SCHEMBL10280536 | 0.92 | DGAT2 (0.34) | DGAT2CACNA1HCACNA1GCACNA1ICNR2 | |
| SCHEMBL14470569 | 0.91 | DGAT2 (0.33) | DGAT2CACNA1HCACNA1GCACNA1ICNR2 | |
| SCHEMBL10280361 | 0.91 | KLKB1 (0.35) | SLC2A1SLC2A3SLC2A4SLC2A2P2RY12 | |
| SCHEMBL10280395 | 0.87 | DHODH (0.37) | SLC2A1SLC2A3SLC2A4SLC2A2DGAT2 | |
| SCHEMBL10280357 | 0.86 | MGAT2 (0.36) | SLC2A1SLC2A3SLC2A4SLC2A2DGAT2 | |
| SCHEMBL10280399 | 0.86 | SLC2A1 (0.34) | SLC2A1SLC2A3SLC2A4SLC2A2DGAT2 | |
| SCHEMBL5620493 | 0.85 | SLC2A1 (0.36) | SLC2A1SLC2A3SLC2A4SLC2A2GCK | |
| SCHEMBL15147427 | 0.85 | SLC2A1 (0.41) | SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H | |
| SCHEMBL31060075 | 0.85 | SLC2A1 (0.41) | SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278464-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120077991-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, LLC | 2012-03-29 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077991-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | SLC2A1 3522/4885SLC2A3 4067/4885SLC2A4 3985/4885 |
| US-20100168066-A1 | NOVEL INSECTICIDES | DDT, ACHE, CYP4F11 | SLC2A1 4053/4885SLC2A3 4338/4885SLC2A4 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.