Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | PTEN | P60484 | 1/20 | 0.30 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389491 | 0.89 | HDAC3 (0.39) | FFAR1F13A1CYP1A2HSD17B10PTGS1 | |
| SCHEMBL7886118 | 0.81 | AKR1B1 (0.31) | HSD17B10 | |
| SCHEMBL6093157 | 0.80 | KEAP1 (0.34) | KEAP1FFAR1NPSR1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3212670 | 0.77 | — | — | |
| SCHEMBL17336727 | 0.76 | NFKB1 (0.33) | — | |
| SCHEMBL5807277 | 0.75 | EPHX2 (0.33) | — | |
| SCHEMBL12257162 | 0.75 | — | — | |
| SCHEMBL11254152 | 0.72 | KEAP1 (0.36) | KEAP1FFAR1NPSR1F13A1CYP1A2 | |
| SCHEMBL1449062 | 0.69 | — | — | |
| SCHEMBL1323323 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | TYMP, TYMS, ADORA3 | KEAP1 3517/4885FFAR1 1027/4885NPSR1 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.