SCHEMBL1028057

SCHEMBL1028057

CCC(CC)CC(C)CO

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 1/20 0.40
TRPA1 O75762 3/20 0.39
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 2/20 0.31
CNR1 P21554 1/20 0.31
ADRA1A P35348 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25267838 1.00 TSHR (0.46) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL13391793 0.92 TRPA1 (0.47) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL4609548 0.92 TRPA1 (0.47) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL14261872 0.85 TSHR (0.56) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL6855046 0.85 TSHR (0.56) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL18016520 0.84 TSHR (0.45) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL9851955 0.84 TSHR (0.45) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL22042318 0.83 TRPA1 (0.45) TSHRALDH1A1TRPA1TDP1LMNA
SCHEMBL16871884 0.81 ALDH1A1 (0.64) TSHRALDH1A1TDP1LMNAKDM4E
SCHEMBL1049623 0.80 TRPA1 (0.47) TSHRALDH1A1TRPA1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624164-B2 Synthetic thickeners incorporating non-reactive diluents HERCULES LLC (US) 2026-05-12 US disclosed
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof HERCULES LLC (US) 2026-03-31 US disclosed
EP-4192923-B1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2025-10-29 EP disclosed
US-20230323138-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2023-10-12 US disclosed
US-20230257522-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2023-08-17 US disclosed
EP-4192922-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF Hercules LLC (US) 2023-06-14 EP disclosed
US-20220289908-A1 SYNTHETIC THICKENERS INCORPORATING NON-REACTIVE DILUENTS HERCULES LLC (US) 2022-09-15 US disclosed
EP-4007787-A1 SYNTHETIC THICKENERS INCORPORATING NON-REACTIVE DILUENTS Hercules LLC (US) 2022-06-08 EP disclosed
US-8557754-B2 Composition of biodegradable gear oil COUNSEL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-10-15 US disclosed
US-20110207638-A1 COMPOSITION OF BIODEGRADABLE GEAR OIL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-08-25 US disclosed
EP-2274407-A1 A COMPOSITION OF BIODEGRADABLE GEAR OIL Council of Scientific & Industrial Research (IN) 2011-01-19 EP disclosed
WO-2009116082-A1 A COMPOSITION OF BIODEGRADABLE GEAR OIL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2009-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624164-B2 Synthetic thickeners incorporating non-reactive diluents GEMIN4, MAGT1, SETDB1 TSHR 3556/4885ALDH1A1 2580/4885TRPA1 577/4885
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof PHOSPHO1, H1-10, H1-0 TSHR 3461/4885ALDH1A1 4014/4885TRPA1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.