SCHEMBL10280804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10280803	0.91	POLB (0.43)	HSD11B1POLBPDE2APDE10AHDAC1
	SCHEMBL15426486	0.91	HSD11B1 (0.47)	HSD11B1POLBPDE2APDE10AMPL
	SCHEMBL15412915	0.89	POLB (0.42)	HSD11B1POLBPDE2APDE10AALOX5AP
	SCHEMBL15412440	0.89	HSD11B1 (0.48)	HSD11B1POLBPDE2AHDAC1HDAC8
	SCHEMBL9953426	0.87	PDE2A (0.49)	HSD11B1POLBPDE2APDE10A
	SCHEMBL10280741	0.87	POLB (0.43)	HSD11B1POLBPDE2APDE10AHDAC1
	SCHEMBL16002372	0.86	POLB (0.40)	HSD11B1POLBCYP11B2
	SCHEMBL16667035	0.86	POLB (0.42)	HSD11B1POLBPDE2APDE10AALOX5AP
	SCHEMBL10281064	0.86	HSD11B1 (0.41)	HSD11B1POLBPDE2APDE10AALOX5AP
	SCHEMBL116863	0.85	POLB (0.43)	HSD11B1POLBPDE2APDE10ACYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.