Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15187038 | 0.89 | MMP1 (0.36) | CTSDCTSEBACE1MMP1MMP3 | |
| SCHEMBL23110215 | 0.83 | CTSD (0.32) | CTSDCTSEBACE1MMP1MMP3 | |
| SCHEMBL18500173 | 0.83 | CTSD (0.32) | CTSDCTSEBACE1MMP1MMP3 | |
| SCHEMBL1709991 | 0.81 | MMP1 (0.32) | CTSDCTSEBACE1MMP1MMP3 | |
| SCHEMBL18520259 | 0.78 | MMP9 (0.32) | MMP1MMP3MMP9 | |
| SCHEMBL14731637 | 0.78 | DPP4 (0.34) | MMP1MMP3MMP9 | |
| SCHEMBL16310482 | 0.77 | MMP9 (0.36) | MMP1MMP3MMP9 | |
| SCHEMBL22966090 | 0.77 | BACE1 (0.35) | CTSDCTSEBACE1MMP1MMP3 | |
| SCHEMBL15384680 | 0.76 | MMP9 (0.35) | CTSDCTSEBACE1MMP1MMP3 | |
| SCHEMBL17993122 | 0.73 | MMP1 (0.34) | MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021796-A2 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL, INC. (US) | 2012-02-16 | — | — | WO | disclosed |