Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.76 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.76 |
| ▸ | RARA | P10276 | 1/20 | 0.76 |
| ▸ | RARB | P10826 | 1/20 | 0.76 |
| ▸ | RARG | P13631 | 1/20 | 0.76 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.76 |
| ▸ | HTR2A | P28223 | 1/20 | 0.76 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.76 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929012 | 0.92 | CYP3A4 (0.76) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| SCHEMBL18388618 | 0.92 | CYP3A4 (0.75) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| SCHEMBL20369287 | 0.90 | CYP3A4 (0.72) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| Gliquidone SCHEMBL29465034 | 0.86 | LMNA (1.00) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| Gliquidone SCHEMBL15669239 | 0.86 | LMNA (1.00) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| Gliquidone SCHEMBL37769 | 0.86 | LMNA (1.00) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| Gliquidone SCHEMBL676846 | 0.85 | LMNA (0.98) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| SCHEMBL25866045 | 0.81 | CYP3A4 (0.75) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| SCHEMBL8216020 | 0.79 | LMNA (0.87) | CYP3A4CYP2C9HPGDLMNAKDM4E | |
| SCHEMBL6165422 | 0.78 | KDM4E (0.60) | CYP3A4CYP2C9HPGDLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-07-12 | — | — | US | disclosed |
| US-20160024011-A1 | Multi-API Loading Prodrugs | ALKERMES PHARMA IRELAND LTD (IE) | 2016-01-28 | — | — | US | disclosed |
| US-20120202823-A1 | Multi-API Loading Prodrugs | ALKERMES, INC. | 2012-08-09 | — | — | US | disclosed |
| WO-2012088441-A1 | MULTI- API LOADING PRODRUGS | ALKERMES, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024011-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | CYP3A4 69/4885CYP2C9 30/4885HPGD 2055/4885 |
| US-20120202823-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | CYP3A4 69/4885CYP2C9 30/4885HPGD 2055/4885 |
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | AADAC, PAICS, ABCG2 | CYP3A4 69/4885CYP2C9 30/4885HPGD 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.