Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 4/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10556416 | 0.84 | APOBEC3A (0.72) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL29793338 | 0.83 | KDM4E (0.52) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| Bromide SCHEMBL9056128 | 0.82 | APOBEC3A (0.70) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL29793250 | 0.80 | BBOX1 (0.50) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL9784661 | 0.79 | APOBEC3A (0.49) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL15956584 | 0.78 | KDM4E (0.52) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL21694114 | 0.78 | APOBEC3A (0.47) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL21694118 | 0.78 | APOBEC3A (0.51) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL15956729 | 0.77 | ALDH1A1 (0.48) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT | |
| SCHEMBL15956347 | 0.77 | APOBEC3A (0.46) | KDM4EAPOBEC3AAPOBEC3GLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719768-B1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORP (JP) | 2012-04-25 | — | — | EP | disclosed |