Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 4/20 | 0.70 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10556416 | 0.98 | APOBEC3A (0.72) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| SCHEMBL10281171 | 0.82 | KDM4E (0.53) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| Bromide SCHEMBL1403204 | 0.82 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| SCHEMBL29793338 | 0.82 | KDM4E (0.52) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| SCHEMBL21694118 | 0.80 | APOBEC3A (0.51) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| SCHEMBL3367030 | 0.79 | APOBEC3A (0.54) | APOBEC3AAPOBEC3GLMNASLC18A3CTDSP1 | |
| SCHEMBL29793250 | 0.78 | BBOX1 (0.50) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| SCHEMBL1598533 | 0.78 | LMNA (0.49) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| SCHEMBL12633575 | 0.78 | SLC18A3 (0.60) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 | |
| SCHEMBL9784661 | 0.78 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GLMNAKDM4ESLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314619-B1 | Epoxy resin mixture | CIBA GEIGY AG (CH) | 1996-07-10 | — | — | EP | disclosed |
| US-4885354-A | Epoxy resin compositions | CIBA-GEIGY CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0314619-A2 | Epoxy resin mixture | CIBA-GEIGY AG (CH) | 1989-05-03 | — | — | EP | disclosed |