Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127919 | 0.89 | HTT (0.54) | SMN1; SMN2LMNAHTTSYKMAPT | |
| SCHEMBL6049741 | 0.86 | HTT (0.59) | SMN1; SMN2LMNAHTTSYKMAPT | |
| SCHEMBL10282200 | 0.86 | LMNA (0.53) | SMN1; SMN2LMNAHTTSYKMAPT | |
| SCHEMBL20136946 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAHTTSYKMAPT | |
| SCHEMBL903426 | 0.84 | HTT (0.63) | SMN1; SMN2LMNAHTTMAPTTGM2 | |
| SCHEMBL17495253 | 0.83 | HTT (0.56) | SMN1; SMN2LMNAHTTSYKMAPT | |
| SCHEMBL20526175 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAHTTSYKMAPT | |
| SCHEMBL4513964 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAHTTSYKMAPT | |
| SCHEMBL28513293 | 0.82 | HTT (0.54) | SMN1; SMN2LMNAHTTSYKMAPT | |
| Glycolic Acid SCHEMBL145941 | 0.82 | HTT (0.58) | SMN1; SMN2LMNAHTTSYKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050899-A1 | POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE | CERULEAN PHARMA INC. (US) | 2012-04-19 | — | — | WO | disclosed |
| WO-2012044832-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | FETZER OLIVER S (US) | 2012-04-05 | — | — | WO | disclosed |