Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | AOC2 | O75106 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281996 | 0.86 | ATM (0.51) | MAPTRPS6KA5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15857985 | 0.84 | RPS6KA5 (0.40) | MAPTRPS6KA5AOC2NPC1RAB9A | |
| SCHEMBL8088160 | 0.83 | MAPT (0.65) | MAPTRPS6KA5AOC2NPC1RAB9A | |
| SCHEMBL18306494 | 0.80 | NPC1 (0.45) | MAPTAOC2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10313053 | 0.80 | SMN1; SMN2 (0.44) | MAPTAOC2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17897213 | 0.80 | LMNA (0.44) | AOC2NPC1RAB9ASMN1; SMN2PDE10A | |
| SCHEMBL1106499 | 0.79 | USP2 (0.40) | RPS6KA5AOC2LMNAKDM4EPOLB | |
| SCHEMBL2929122 | 0.77 | MAPT (0.66) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL19233684 | 0.77 | NTRK1 (0.42) | RPS6KA5ATMKDM4EPOLBMEN1 | |
| SCHEMBL8657015 | 0.76 | MAPT (0.47) | MAPTAOC2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178733-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2012-07-12 | — | — | US | disclosed |
| US-8153670-B2 | Factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090298806-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298806-A1 | FACTOR XA INHIBITORS | TFPI, F12, F11 | MAPT 3722/4885RPS6KA5 4276/4885AOC2 844/4885 |
| US-20120178733-A1 | FACTOR XA INHIBITORS | TFPI, F12, F11 | MAPT 3722/4885RPS6KA5 4276/4885AOC2 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.