Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529636 | 0.76 | RAB9A (0.48) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL529762 | 0.74 | ACHE (0.42) | ACHEKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL22639730 | 0.68 | ACHE (0.51) | ACHEKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL15191122 | 0.67 | MAPK1 (0.63) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL15191140 | 0.66 | MEN1 (0.49) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL2104807 | 0.65 | JAK2 (0.57) | — | |
| SCHEMBL13118498 | 0.65 | ACHE (0.61) | ACHEKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL1088557 | 0.64 | MRGPRX1 (0.51) | ACHEKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL22201647 | 0.64 | HPGD (0.54) | ACHEKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL1088730 | 0.64 | MRGPRX1 (0.50) | ACHEKDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | disclosed |