Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 6/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639730 | 0.82 | ACHE (0.51) | HPGDALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3460111 | 0.78 | GBA1 (0.77) | HPGDALDH1A1PDE5APTGS1TBXAS1 | |
| SCHEMBL3971152 | 0.77 | KDM4E (0.45) | HPGDALDH1A1MAPTPDE5AKDM4E | |
| SCHEMBL3976155 | 0.77 | KDM4E (0.52) | HPGDALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL3327772 | 0.76 | PRKCD (0.54) | HPGDALDH1A1KDM4EACHELMNA | |
| SCHEMBL10134675 | 0.74 | DRD2 (0.47) | HPGDALDH1A1KDM4ETSHRACHE | |
| SCHEMBL3974946 | 0.74 | DRD2 (0.49) | ALDH1A1MAPTKDM4E | |
| SCHEMBL3460750 | 0.73 | ACP1 (0.74) | ALDH1A1MAPTPDE5APTGS1TBXAS1 | |
| SCHEMBL1088557 | 0.72 | MRGPRX1 (0.51) | HPGDALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL22639883 | 0.72 | LMNA (0.60) | HPGDALDH1A1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |