Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | CD63 | P08962 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13155401 | 0.81 | L3MBTL1 (0.42) | NUDT1L3MBTL1HTR2CTNKS | |
| SCHEMBL104884 | 0.79 | HTR2C (0.47) | NUDT1L3MBTL1HTR2CTNKS | |
| SCHEMBL13693180 | 0.79 | L3MBTL1 (0.38) | NUDT1L3MBTL1HTR2CTNKS | |
| SCHEMBL19630404 | 0.77 | NUDT1 (0.45) | NUDT1L3MBTL1DYRK1APIK3R1PIK3CA | |
| SCHEMBL19616357 | 0.76 | L3MBTL1 (0.33) | NUDT1L3MBTL1SYK | |
| SCHEMBL19629178 | 0.76 | L3MBTL1 (0.33) | NUDT1L3MBTL1 | |
| SCHEMBL8240995 | 0.76 | L3MBTL1 (0.35) | NUDT1L3MBTL1 | |
| SCHEMBL104697 | 0.76 | L3MBTL1 (0.35) | NUDT1L3MBTL1 | |
| SCHEMBL19629179 | 0.75 | L3MBTL1 (0.33) | NUDT1L3MBTL1 | |
| SCHEMBL103804 | 0.75 | NUDT1 (0.46) | NUDT1L3MBTL1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460805-A1 | FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION | Oncotherapy Science, Inc. (JP) | 2012-06-06 | — | — | EP | disclosed |