Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | CD63 | P08962 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15687846 | 0.80 | L3MBTL1 (0.47) | NUDT1L3MBTL1TNKSHTR2CSYK | |
| SCHEMBL19865160 | 0.77 | L3MBTL1 (0.53) | NUDT1L3MBTL1TNKSHTR2CSYK | |
| SCHEMBL10282182 | 0.77 | NUDT1 (0.41) | NUDT1L3MBTL1DYRK1ATNKSPIK3R1 | |
| SCHEMBL24995375 | 0.74 | L3MBTL1 (0.42) | NUDT1L3MBTL1TNKSHTR2CAURKA | |
| SCHEMBL24174447 | 0.74 | L3MBTL1 (0.42) | NUDT1L3MBTL1TNKSHTR2C | |
| SCHEMBL24156570 | 0.74 | L3MBTL1 (0.42) | NUDT1L3MBTL1TNKSHTR2C | |
| SCHEMBL19629293 | 0.74 | L3MBTL1 (0.39) | NUDT1L3MBTL1TNKSSYKCD63 | |
| SCHEMBL15688262 | 0.73 | NUDT1 (0.55) | NUDT1L3MBTL1DYRK1ATNKSPIK3R1 | |
| SCHEMBL24033106 | 0.72 | ALDH1A1 (0.36) | NOS3NOS1NOS2ADORA2A | |
| SCHEMBL3525899 | 0.72 | NUDT1 (0.52) | NUDT1L3MBTL1DYRK1ATNKSADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| WO-2017200857-A1 | METHODS FOR USING TRIAZOLO-PYRAZINYL SOLUBLE GUANYLATE CYCLASE ACTIVATORS IN FIBROTIC DISORDERS | MERCK SHARP & DOHME CORP. (US) | 2017-11-23 | — | — | WO | disclosed |