Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789782 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTMAOB | |
| SCHEMBL1011335 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTMAOB | |
| SCHEMBL865619 | 0.72 | HTR2A (0.41) | ALDH1A1KDM1AMAOAMAOB | |
| SCHEMBL23714201 | 0.71 | HTR5A (0.37) | MAPT | |
| SCHEMBL31059284 | 0.71 | HTR5A (0.37) | MAPT | |
| SCHEMBL27494959 | 0.71 | CA12 (0.33) | ALDH1A1MAPTMAOB | |
| Hydrochloric Acid SCHEMBL1786173 | 0.70 | KDM1A (0.41) | ALDH1A1KDM1AMAOAMAOB | |
| SCHEMBL5334825 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL3733923 | 0.69 | HDAC9 (0.38) | MAPT | |
| Hydrochloric Acid SCHEMBL2084296 | 0.68 | ALDH1A1 (0.42) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420491-A1 | 3 , 5-substitued piperidine compounds as renin inhibitors | Novartis AG (CH) | 2012-02-22 | — | — | EP | disclosed |