Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 2/20 | 0.33 |
| ▸ | ARG2 | P78540 | 2/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334825 | 0.75 | ALDH1A1 (0.40) | HDAC9GAAMAPT | |
| SCHEMBL30868729 | 0.75 | MME (0.37) | HDAC9MMEMMP8 | |
| Hydrochloric Acid SCHEMBL2084296 | 0.74 | ALDH1A1 (0.42) | HDAC9GAAMAPT | |
| SCHEMBL29476532 | 0.72 | HDAC9 (0.44) | HDAC9DPP9DPP7CXCR5MME | |
| SCHEMBL122942 | 0.72 | HDAC9 (0.44) | HDAC9DPP9DPP7CXCR5MME | |
| Hydrochloric Acid SCHEMBL1168670 | 0.71 | HDAC9 (0.43) | HDAC9DPP9DPP7CXCR5MME | |
| SCHEMBL6830859 | 0.70 | LMNA (0.40) | HDAC9MAPTMMP8 | |
| SCHEMBL10282913 | 0.69 | ALDH1A1 (0.41) | MAPT | |
| SCHEMBL27494959 | 0.69 | CA12 (0.33) | MAPTPRCP | |
| SCHEMBL7038616 | 0.69 | ALDH1A1 (0.35) | HDAC9GAAMAPTCXCR5MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000535-B2 | Template-fixed peptidomimetics | POLYPHOR LTD. (CH) | 2018-06-19 | — | — | US | claimed |
| US-10000535-B2 | Template-fixed peptidomimetics | POLYPHOR LTD. (CH) | 2018-06-19 | — | — | US | disclosed |
| US-20140107031-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS | POLYPHOR LTD. (CH) | 2014-04-17 | — | — | US | disclosed |
| US-8633163-B2 | Template-fixed peptidomimetics | POLYPHOR LTD. (CH) | 2014-01-21 | — | — | US | disclosed |
| US-20100093644-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS | POLYPHOR LTD. (CH) | 2010-04-15 | — | — | US | disclosed |
| EP-2114986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS | Polyphor Ltd. (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008092281-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS | POLYPHOR LTD. (CH) | 2008-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107031-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS | CCR10, CXCR3, CCR5 | HDAC9 2835/4885GAA 2377/4885MAPT 2455/4885 |
| US-10000535-B2 | Template-fixed peptidomimetics | CCR10, CXCR3, CCR5 | HDAC9 2835/4885GAA 2377/4885MAPT 2455/4885 |
| US-20100093644-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS | CCR10, CXCR3, CCR1 | HDAC9 3050/4885GAA 2213/4885MAPT 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.